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Vastarel (TRIMETAZIDINE) is a drug used for the treatment of ischaemic heart disease (angina pectoris, sequelae of infarction). Trimetazidine is an anti-ischemic (anti-anginal) metabolic agent, that improves myocardial glucose utilization through inhibition of Fatty acid metabolism.

 

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Vastarel Description

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ENTERAL NUTRITION FOR CRITICALLY ILL

Enteral feeding includes both oral feeding as well as tube feeding. When oral feeding is insufficient or not feasible, or when a current situation causing depletion is likely to be extended for a long period of time or where treatment is likely to prelude adequate oral intake or absorption for a significant time, tube feeding enables one to maintain a good nutritional status. Tube feeding may be instituted as a temporary measure or in some cases even permanently for the remainder of the patient\'s life.

The tube feeding should have all nutrients in required amounts and should be a liquid with low viscosity to enable it to pass through the tube easily by gravity flow.

Enteral Feeding vs Parenteral Feeding

Studies have shown that parenteral feeding is associated with more complications, both metabolic and septic. Continuous regulated enteral nutrition with elemental diet has been suggested as an alternative to total parenteral nutrition and the effect of diet on body composition has been found to be the same in both cases. Enteral feeding is also cheaper in comparison with parenteral feeding.

Indications for Enteral Nutrition

1. Neurological or psychiatric disorders, coma, severe depression.

2. Oropharyngeal or oesophageal disorders.

3. Trauma, fractures of head and neck.

4. Gastrointestinal disorders, fistulae, short bowel syndromes.

5. Head injuries and burns.

6. Renal or liver failure.

In critically ill trauma patients, due to raised metabolism and extraneous losses in terms of haemorrhage, exudates or fistulae, a patient needs the following:

High calories: 3000-3500/day

Proteins: 100-120 g

Adequate in all nutrients especially potassium.

The tube feed can be modified according to the status of the patient, such as a diabetic, renal or hepatic tube feed.

Technique of administration of feed is:

1. Nasogastric

2. Gastrostomy

3. Oesophagostomy

4. Jejunostomy.

The feeds are of following types:

1. Blenderized: Natural foods are blenderized and made into a liquid form.

2. Polymeric: Low residue foods like proteins from whole milk (casein), polysaccharides, disaccharides like sucrose or monosaccharides like glucose and vegetable oil or medium chain triglycerides (MCT).

3. Monomeric (elemental): Hydrolysed casein or crystalline amino acid, vegetable or MCT oil, glucose and dextrins supplemented with vitamins and minerals.

The formula is selected as given below:

1. Calories: Standard formula = 1 kcal/ml; high calorie formula = 1.5 kcal/ml.

2. Proteins: 9-24% of total calories or depending upon patients\' physiological status.

3. Fats: 1- 47% of calories.

4. Carbohydrates: Carbohydrate content varies, as it affects the osmolality of the solution.

The ingredients may be:

1. Blenderized: Milk, chicken, egg, oil, sugar, vegetables, fruit, flour or any other natural food.

2. Polymeric: Milk casein, oil, lactose, sucrose.

3. Elemental: Amino acids, glucose, sucrose, oil.

Technique of formula administration is given here:

All tube feedings begin with limited quantities of the formula containing 0.5 kcal/ml to avoid diarrhoea. The first feeding is 30 ml/hr of formula, and gradually the quantity is increased to 40 ml/hr, 50 ml/hr or 60 ml/hr. Flush tube every 4 hours with 30 ml of water. The strength of feed should be 1 kcal/ml. While feeding, the head and thorax of the patient should be elevated at an angle of at least 30° for at least 30 minutes after the feeding. Continuous feeding by infusion method is more beneficial.

Other methods of formula administration:

1. Fluoroscopic placement of nasojejunal tube.

2. Nutromat system - continuous administration (battery or power operated).

3. Mobile infusion system for continuous jejunostomy feeding.

The tube feed can be modified according to the status of the patient, such as a diabetic, renal or hepatic tube feeds.

*8/356/5*

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PROSTATE CANCER


This is one of the specifically male cancers about which there has been most publicity in recent years. There has been debate about whether men should be routinely screened for prostate cancer, although so far no action has been taken to put this into effect. It is a cancer which rarely affects younger men.

 

SEX AND PUBERTY: MEN’S CANCER
An unfortunate byproduct of the guilt created about masturbation is that the whole genital area can become off-limits. The 'hands off' policy flies in the face of good preventive health measures.

The two sexes: The "G" Spot
In Germany in the 1940s an obstetrician and gynaecologist called Ernst Grafenburg, researching new methods of birth control, claimed to have discovered a new, internal zone of erogenous feeling in the women he was studying. This sparked a controversy, which has become more prevalent in recent years, concerning whether or not these male and female G (Grafenburg) spots in fact exist.
 

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