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Category: Antibiotics

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Rulide

Rulide (ROXITHROMYCIN) is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Rulide is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring. It is also currently undergoing clinical trials for the treatment of male-pattern hair loss.

Rulide prevents bacteria from growing, by interfering with their protein synthesis. Rulide binds to the subunit 50S of the bacterial ribosome, and thus inhibits the translocation of peptides. Rulide has similar antimicrobial spectrum as erythromycin, but is more effective against certain gram-negative bacteria, particularly Legionella pneumophila.

 

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Rulide Description

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MENIERE\'S DISEASE: NON-SPECIFIC MEASURES TO MANAGE TINNITUS

Tinnitus sufferers need reassurance and explanation of the condition. Many people worry that their tinnitus is a symptom of a brain tumour, cancer, a stroke, approaching insanity or the development of a severe hearing loss. Many people are simply seeking reassurance that no serious condition is present. When given this assurance after appropriate investigation they are no longer bothered by tinnitus, although when they think about it they can still hear it.

If the tinnitus is caused by noise induced hearing loss, it is obvious that very loud continuous sound should be avoided. However, the approach sometimes adopted of as near complete sound avoidance as possible, is now considered undesirable in light of newer theories of desensitization.

Heavy caffeine intake and smoking definitely seem to aggravate most tinnitus. Smoking should cease completely (for other health reasons as well, of course). A one month trial of total caffeine avoidance is worth trying, i.e. avoiding anything which may contain caffeine such as coffee, tea, chocolate or cola drinks.

Review medications being taken, as some (e.g. aspirin, anti-inflammatory, etc.), can exacerbate tinnitus.

Check whether any of these above factors that are known or suspected to aggravate tinnitus are present. It may involve checking any medication taken with your general practitioner.

If you suspect there is a link between any of the above and your tinnitus, seek expert advice on appropriate management techniques from your doctor or audiologist. One of the biggest problems in coping with tinnitus is that tension and anxiety seem to make it appear louder and more overwhelming.

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PROSTATE CANCER


This is one of the specifically male cancers about which there has been most publicity in recent years. There has been debate about whether men should be routinely screened for prostate cancer, although so far no action has been taken to put this into effect. It is a cancer which rarely affects younger men.

 

SEX AND PUBERTY: MEN’S CANCER
An unfortunate byproduct of the guilt created about masturbation is that the whole genital area can become off-limits. The 'hands off' policy flies in the face of good preventive health measures.

The two sexes: The "G" Spot
In Germany in the 1940s an obstetrician and gynaecologist called Ernst Grafenburg, researching new methods of birth control, claimed to have discovered a new, internal zone of erogenous feeling in the women he was studying. This sparked a controversy, which has become more prevalent in recent years, concerning whether or not these male and female G (Grafenburg) spots in fact exist.
 

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