Periactin

Periactin (CYPROHEPTADINE) is a piperidine antihistamine. Unlike other antihistamines, this drug also antagonizes serotonin receptors. This action makes Cyproheptadine useful in conditions such as vascular headache and anorexia. Cyproheptadine does not prevent the release of histamine but rather competes with free histamine for binding at HA-receptor sites. Cyproheptadine competitively antagonizes the effects of histamine on HA-receptors in the GI tract, uterus, large blood vessels, and bronchial smooth muscle. Most antihistamines possess significant anticholinergic properties, but Cyproheptadine exerts only weak anticholinergic actions. Blockade of central muscarinic receptors appears to account for Cyproheptadine\\\'s antiemetic effects, although the exact mechanism is unknown. Cyproheptadine also competes with serotonin at receptor sites in smooth muscle in the intestines and other locations. Antagonism of serotonin on the appetite center of the hypothalamus may account for Cyproheptadine\\\'s ability to stimulate appetite. Cyproheptadine also has been used to counter vascular headaches, which many believe are caused by changes in serotonin activity, however it is unclear how Cyproheptadine exerts a beneficial effect on this condition. For treatment of perennial and seasonal allergic rhinitis, vasomotor rhinitis, allergic conjunctivitis due to inhalant allergens and foods, mild uncomplicated allergic skin manifestations of urticaria and angioedema, amelioration of allergic reactions to blood or plasma, cold urticaria, dermatographism, and as therapy for anaphylactic reactions adjunctive to epinephrine.

SELF-HELP MEASURES FOR LIVING WITH VERTIGO

Although medical treatment and exercises can help greatly, some people may be left with a certain amount of long-lasting dizziness. People who have learned to cope with long-term dizziness usually say that there are two important ways to prevent it becoming a really serious problem.

The first is to avoid high levels of stress. Stress and tension can increase the likelihood of becoming dizzy, and can make dizziness worse. If you are under a lot of pressure or find it difficult to relax, you should consider joining relaxation or stress management classes. Courses of this sort are available as part of the adult education program in most areas.

The second important principle is to try not to let the dizziness change your lifestyle too much. You may want to arrange for someone to be available to support you if you have a severe attack or you may need to rest or keep to quiet indoor activities on your bad days. You might also want to take a stick or shopping jeep with you when you go out so that you can lean on them if you feel a bit giddy. But try not to cut down on activities you really enjoy.

Some people find themselves restricting all sorts of work and social contacts in case they have a dizzy spell in public, or avoiding some physical activities in case they provoke dizziness. But by learning to cope with the dizziness you can continue to enjoy a full and active life. After all, although dizziness can be frightening, unpleasant or even embarrassing, it is not actually dangerous. Once family, friends and colleagues know about your problems and how to help, they are likely to be very understanding and may be able to give you the extra help you need to maintain your lifestyle. So do not allow the vertigo to get in your way. With help you can find practical solutions to most of the problems caused by dizziness and its effect on your life can be kept to a minimum.

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GENERAL HEALTH

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